Description

Dutasteride is used to treat men with symptoms of benign prostatic hyperplasia (BPH), a condition where the prostate gland is enlarged. This enlargement can cause urinary problems such as frequent urination, weak urine flow, or incomplete bladder emptying. Dutasteride may be used alone or in combination with tamsulosin (Flomax®) to manage these symptoms.

Dutasteride works by blocking the enzyme 5-alpha-reductase, which converts testosterone into a hormone that promotes prostate growth. By inhibiting this enzyme, dutasteride reduces prostate size. The effect of dutasteride persists only as long as the medication is taken; stopping the medication will result in the prostate regrowing.

Dosage Forms

• Capsule, Liquid Filled

Before Using

• Allergies: Inform your doctor of any unusual or allergic reactions to this or other medicines, including allergies to foods, dyes, or preservatives.
• Pediatric Use: Not recommended for children. Safety and efficacy have not been established.
• Geriatric Use: No geriatric-specific problems have been identified that limit its use in the elderly.
• Breastfeeding: There are no adequate studies to determine the risk of using this medication while breastfeeding. Weigh the potential benefits against the risks.

Drug Interactions

• Not Recommended With: Ceritinib, Itraconazole.
• Use With Caution: Cimetidine, Ciprofloxacin, Diltiazem, Ketoconazole, Ritonavir, Verapamil.
• Food, Alcohol, and Tobacco: Discuss with your healthcare provider the use of this medication with food, alcohol, or tobacco.

Other Medical Problems

• Liver Disease: Use with caution as it may be affected by slower removal from the body.

Proper Use

• Administration: Take exactly as prescribed. Swallow capsules whole; do not crush, chew, or open. It can be taken with or without food.
• Dosage: Typically 0.5 mg once daily for BPH. Follow your doctor’s specific instructions.

Missed Dose

• Take as soon as possible unless it's almost time for your next dose. Do not double doses.

Storage

• Store at room temperature, away from heat, moisture, and light. Do not freeze. Keep out of reach of children. Dispose of unused medicine properly.

Precautions

• Handling by Women: Women of childbearing potential should avoid handling dutasteride capsules due to the risk of birth defects. If contact occurs, wash the affected area immediately.
• Blood Donation: Men should not donate blood for 6 months after their last dose due to the risk of transferring the medication to pregnant women.
• Prostate Cancer Risk: May increase the risk of high-grade prostate cancer. Discuss this with your doctor.
• PSA Test: Dutasteride may affect PSA test results used to detect prostate cancer.

Side Effects

Serious Side Effects:

• Chest pain or discomfort
• Dilated neck veins
• Extreme fatigue
• Irregular breathing or heartbeat
• Swelling of face, fingers, feet, or legs
• Trouble breathing
• Weight gain

Other Possible Side Effects:

• Less Common: Abnormal ejaculation, decreased sexual interest, performance issues, impotence, breast pain or swelling.
• Rare: Skin issues, cough, difficulty swallowing, dizziness, fast heartbeat, hives, puffiness, redness, unusual tiredness or weakness.

Reporting Side Effects

• Contact your doctor for medical advice about side effects. Report any adverse effects to the FDA.

Note: 

The brand name displayed above is specific to this product. Brand names can vary depending on the manufacturer. Always consult your healthcare provider to ensure that the product you choose is appropriate for your condition.